Filler Face-Off: sculptra vs radiesse at the genetic level
NCT ID NCT05620043
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how two different dermal fillers—Sculptra and Radiesse Plus—change gene activity in the skin. Researchers took small skin samples from 21 people after treatment to measure genes related to collagen, elastin, and skin repair. The goal was to understand which filler might better support skin health at a molecular level.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Poly-L-lactic acid (Sculptra) and calcium hydroxylapatite (Radiesse Plus)
- What this could lead to
- If successful, this could help doctors choose which filler is better for stimulating collagen and skin repair based on genetic markers.
- What could go wrong
- This is a very small, early study (21 people) looking at gene changes, not actual cosmetic outcomes. Results may not predict real-world effectiveness or apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Miami Dermatology & Laser Institute
Miami, Florida, 33173, United States
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