Filler Face-Off: sculptra vs radiesse at the genetic level
NCT ID NCT05620043
First seen Apr 24, 2026 · Last updated Jun 23, 2026 · Updated 17 times
Summary
This study looked at how two different dermal fillers—Sculptra and Radiesse Plus—change gene activity in the skin. Researchers took small skin samples from 21 people after treatment to measure genes related to collagen, elastin, and skin repair. The goal was to understand which filler might better support skin health at a molecular level.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Miami Dermatology & Laser Institute
Miami, Florida, 33173, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Poly-L-lactic acid (Sculptra) and calcium hydroxylapatite (Radiesse Plus)
What this could lead to
If successful, this could help doctors choose which filler is better for stimulating collagen and skin repair based on genetic markers.
What could go wrong
This is a very small, early study (21 people) looking at gene changes, not actual cosmetic outcomes. Results may not predict real-world effectiveness or apply to everyone.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.