ICU phosphate study: less may be more

NCT ID NCT07288944

Not yet recruiting Knowledge-focused Sponsor: Caboolture Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will compare two standard approaches for replacing phosphate in critically ill patients in the intensive care unit (ICU). One approach starts replacement at a higher phosphate level (liberal), the other at a lower level (restrictive). The goal is to see if the restrictive approach reduces the amount of phosphate given while keeping patients just as healthy. About 2,400 adult ICU patients will take part, and the main measure is how many days they are alive and out of the ICU within 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: phosphate replacement protocols (liberal vs. restrictive)
What this could lead to: If successful, this could show that a more restrictive phosphate replacement strategy is safe and reduces unnecessary treatment in ICU patients.
What could go wrong: This is an early-stage protocol comparison, not a test of a new drug. The results may not apply to all ICU settings, and the study hasn't started recruiting yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CRITICAL CARE, INTENSIVE CARE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hypophosphatemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL CARE, INTENSIVE CARE HYPOPHOSPHATEMIA PHOSPHATE DEFICIENCY PROTOCOL OPTIMIZATION

More trials for these conditions

Other studies related to the condition(s) this trial covers.