Could a pill combo replace harsh chemo for leukemia patients?
NCT ID NCT04801797
First seen Nov 15, 2025 · Last updated May 31, 2026 · Updated 30 times
Summary
This study compares a newer, targeted drug combination (venetoclax and azacitidine) to standard chemotherapy for adults newly diagnosed with acute myeloid leukemia (AML). About 172 fit adults will be randomly assigned to one of the two treatments. The goal is to see if the newer combo can control the disease as well as or better than standard chemo, with potentially fewer side effects.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atrium Health Levine Cancer Institute
Charlotte, North Carolina, 28204, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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City of Hope
Duarte, California, 91010, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
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Ohio State University Medical Center
Columbus, Ohio, 43210, United States
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Stanford Cancer Center
Palo Alto, California, 94304, United States
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University of California - Davis
Sacramento, California, 95817, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Conditions
Explore the condition pages connected to this study.