New scan method could catch 20% more hidden cancers

NCT ID NCT06527027

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares three methods for reading CT and MRI scans of lymph nodes to see which best detects cancer. The new method, LN-RADS, may find small metastases that current guidelines miss. Researchers will enroll 1,000 people with known or suspected cancer who need a lymph node biopsy. The goal is to see if LN-RADS is more accurate than the standard RECIST 1.1 and the newer Node-RADS systems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If LN-RADS works better, doctors could detect more lymph node metastases, leading to more accurate cancer staging and better treatment decisions.
What could go wrong
This is a diagnostic comparison study, not a treatment trial. Even if LN-RADS is more accurate, it may not improve patient outcomes or be adopted widely.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Copernicus Memorial Hospital

    RECRUITING

    Lodz, 93-513, Poland

  • Doradztwo i Zarządzanie w Opiece Zdrowotnej A.K. Sp.z o.o

    ACTIVE_NOT_RECRUITING

    Warsaw, Poland

  • Independent Public Healthcare Centre (SPZOZ) , University Clinical Hospital No. 2 of the Medical University of Łódź

    ACTIVE_NOT_RECRUITING

    Lodz, Poland

  • Maria Skłodowska-Curie National Research Institute of Oncology - National Research Institute

    ACTIVE_NOT_RECRUITING

    Krakow, Poland

  • Maria Skłodowska-Curie National Research Institute of Oncology - National Research Institute

    ACTIVE_NOT_RECRUITING

    Warsaw, Poland

  • Professor Orłowski Hospital in Warsaw , Independent Public Healthcare Centre

    ACTIVE_NOT_RECRUITING

    Warsaw, Poland

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