Could a tiny dye dose prevent bile duct injuries during gallbladder removal?

NCT ID NCT07195331

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares two doses of a dye called indocyanine green (ICG) given before laparoscopic gallbladder removal. The dye helps surgeons see the bile ducts clearly, which may reduce the risk of accidental injury. One group gets the standard dose hours before surgery; the other gets a much lower dose just 15–30 minutes before. The study will enroll 122 adults in Spain to see if the lower dose works just as well.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

indocyanine green (ICG)

What this could lead to

If successful, this could make a safer, more convenient dye-dosing routine standard for gallbladder surgery, potentially reducing bile duct injuries.

What could go wrong

This is a small, early-phase trial (122 participants) comparing two doses; it may not show a clear difference, and results may not apply to all patients or surgical settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholelithiasis polyp of gallbladder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Universitario de Salamanca

    RECRUITING

    Salamanca, Salamanca, 37006, Spain

  • Hospital Virgen de la Concha

    NOT_YET_RECRUITING

    Zamora, Zamora, 49022, Spain