New gut cleaner could match standard infection prevention in colon surgery

NCT ID NCT07180615

First seen Nov 01, 2025 · Last updated May 29, 2026 · Updated 32 times

Summary

This study compares two gut-cleaning treatments given before colon surgery to see if a newer drug (rifaximin) works as well as the standard combination (neomycin and metronidazole) at preventing surgical site infections. About 458 adults having planned colon surgery will take one of the two treatments the day before surgery. Researchers will track infections, deaths, and hospital stay length for 30 days after surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kantonsspital Aarau

    Aarau, 5001, Switzerland

  • Kantonsspital St. Gallen

    Sankt Gallen, 9007, Switzerland

  • Luzerner Kantonsspital

    Lucerne, 6006, Switzerland

  • Stadtspital Triemli

    Zurich, 8063, Switzerland

Conditions

Explore the condition pages connected to this study.