Timing is everything: new trial aims to save lives from immune storm

NCT ID NCT07497438

First seen Apr 04, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This study compares giving the drug etoposide early versus waiting when treating severe hemophagocytic lymphohistiocytosis (HLH) in intensive care. HLH is a life-threatening overreaction of the immune system that can cause organ failure. The goal is to see if early treatment reduces organ damage and improves survival in 176 adult ICU patients.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Intensive Care Unit - Avicenne Hospital, Assistance Publique des Hôpitaux de Paris

    Bobigny, 93000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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