New study aims to find the best way to stop antidepressants safely

NCT ID NCT07393919

First seen Feb 06, 2026 · Last updated May 12, 2026 · Updated 9 times

Summary

This study compares two methods for safely stopping antidepressants in adults whose depression is in remission. Participants will be randomly assigned to either a standard gradual dose reduction or a more precise 'hyperbolic' reduction over several weeks. The goal is to see which approach helps more people successfully stop their medication without restarting it or experiencing severe withdrawal.

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