New dosing method may improve infection prevention in overweight surgery patients

NCT ID NCT06005168

First seen Feb 01, 2026 · Last updated May 20, 2026 · Updated 14 times

Summary

This study looked at how to best dose an antibiotic (cefazolin) in overweight patients having surgery. The goal was to see if using a patient's body composition (like fat distribution) instead of just body weight leads to better antibiotic levels in blood and fat tissue to prevent infections. Researchers compared the standard weight-based dosing to a new body-composition method in 57 adults. The study did not test a new treatment but aimed to improve how we give existing antibiotics.

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Contacts and locations

Locations

  • University of Michigan Hospital

    Ann Arbor, Michigan, 48108, United States

Conditions

Explore the condition pages connected to this study.