New drug cocktail aims to wipe out stomach tumors before surgery

NCT ID NCT07151209

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 33 times

Summary

This study tests whether a combination of two immunotherapy drugs (Iparomlimab and Tuvonralimab) plus chemotherapy and a targeted therapy can shrink locally advanced stomach or gastroesophageal junction cancer in patients with specific genetic markers (MSI-H/dMMR). The goal is to make the tumor removable by surgery and achieve a complete response. About 20 adults who have not had prior treatment for advanced disease will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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