New combo therapy aims to reignite immune attack on drug-resistant tumors

NCT ID NCT03474497

First seen Feb 01, 2026 · Last updated Jun 09, 2026 · Updated 13 times

Summary

This study is for adults with advanced lung, skin, kidney, or head-and-neck cancers that have stopped responding to standard immunotherapy. The treatment combines an immune-boosting drug injected directly into a tumor, targeted radiation, and an immunotherapy drug (pembrolizumab). The goal is to see if this triple approach can shrink tumors throughout the body and improve disease control. About 18 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UC Davis Medical Center

    Sacramento, California, 95817, United States

  • University of California Davis Medical Center

    Sacramento, California, 97817, United States

Conditions

Explore the condition pages connected to this study.