Experimental combo targets Hard-to-Treat melanoma

NCT ID NCT02706353

First seen Nov 21, 2025 · Last updated May 09, 2026 · Updated 25 times

Summary

This study tested a new drug combination for people with metastatic melanoma (cancer that has spread). The goal was to find the safest dose of an experimental drug (APX005M) given directly into tumors, along with a standard immunotherapy (pembrolizumab) given through the blood. The study aimed to see if this combination could help control the cancer. It included 34 participants and was stopped early.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.