New cocktail of four drugs takes on advanced colorectal cancer

NCT ID NCT07395063

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing a combination of four drugs—irinotecan liposome, capecitabine, bevacizumab, and camrelizumab—as a second or later treatment for people with metastatic colorectal cancer. The study will enroll 68 participants and measure how long the disease stays under control. The goal is to see if this mix can shrink tumors and delay progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
irinotecan liposome, capecitabine, bevacizumab, and camrelizumab
What this could lead to
If this works, it could offer a new treatment option for people with metastatic colorectal cancer who have already tried one line of therapy.
What could go wrong
This is a small, early-phase trial with no control group, so results may not be definitive. The combination of drugs may cause significant side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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