Aggressive combo attack aims to wipe out tough prostate cancer
NCT ID NCT03436654
First seen Jan 06, 2026 · Last updated May 05, 2026 · Updated 20 times
Summary
This study is for men with very high-risk or early-spread prostate cancer. It combines hormone-lowering injections, study drugs (abiraterone, prednisone, apalutamide), surgery, and possibly radiation to shrink the cancer as much as possible before surgery. The goal is to lower PSA to undetectable levels and reduce the chance of cancer coming back. About 102 men are taking part in this phase 2 trial.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack (Limited Protocol Activities)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, 10604, United States
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Northwestern University
Evanston, Illinois, 60208, United States
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University of Chicago
Chicago, Illinois, 60637, United States
Conditions
Explore the condition pages connected to this study.