Cancer cocktail study halted: early hopes dashed for Triple-Drug combo
NCT ID NCT02959437
First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 27 times
Summary
This study tested a combination of three drugs (azacitidine, pembrolizumab, and epacadostat) in people with advanced solid tumors, including lung and colorectal cancers that had stopped responding to standard treatments. The goal was to see if the combination was safe and could shrink tumors. The study was terminated early, meaning it did not meet its goals or had safety concerns. About 70 people participated, and the main focus was on side effects and tumor response.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SOLID TUMORS are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Churchill Hospital
Oxford, Ox37le, United Kingdom
-
City of Hope National Medical Center
Duarte, California, 91010, United States
-
MD Anderson Cancer Center
Houston, Texas, 77030, United States
-
Sarah Cannon
Nashville, Tennessee, 37203, United States
-
The University of Chicago
Chicago, Illinois, 60637, United States
-
Univ De Navarra
Pamplona, 31008, Spain
-
University College London Hospitals (Uclh)
London, W1t7ha, United Kingdom
-
University of California San Diego
La Jolla, California, 92093, United States
-
University of Pennsylvania Health System
Philadelphia, Pennsylvania, 19014, United States
-
University of Washington
Seattle, Washington, 98109, United States
-
Vall D Hebron Univ
Barcelona, 08035, Spain
-
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232, United States
Conditions
Explore the condition pages connected to this study.