Double radiation attack aims to blast stubborn thyroid cancer
NCT ID NCT04892303
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests a new way to treat thyroid cancer that has returned or spread. It combines two types of radiation—external beam radiation and radioactive iodine—to deliver a stronger dose to tumors. The goal is to see if this combination is safe and can give a higher radiation dose than either treatment alone. The trial includes adults with a specific type of thyroid cancer that still takes up iodine and cannot be fully removed by surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- external beam radiation plus radioactive iodine (131-I)
- What this could lead to
- If successful, this approach could allow higher radiation doses to thyroid cancer tumors, potentially improving tumor control without increasing side effects.
- What could go wrong
- This is an early-phase safety trial with only 48 participants, so effectiveness is not yet proven. There is a risk of serious side effects from the combined radiation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Johns Hopkins SKCCC
RECRUITINGBaltimore, Maryland, 21287, United States
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Other studies related to the condition(s) this trial covers.