New drug duo targets aggressive colon cancer mutation in major trial

NCT ID NCT06008119

First seen Nov 01, 2025 · Last updated Apr 12, 2026 · Updated 25 times

Summary

This study is testing whether a combination of two targeted drugs (tunlametinib and vemurafenib) works better than standard chemotherapy for people with advanced colorectal cancer that has a specific genetic change called BRAF V600E. The trial is for adults whose cancer has continued to grow despite at least one prior treatment. Researchers will measure if the drug combination helps patients live longer without their cancer getting worse.

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Contacts and locations

Locations

  • Beijing Oncology Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.