New attack on Tough-to-Treat colon cancer cells

NCT ID NCT05843188

Summary

This study tests whether adding hydroxychloroquine (an anti-malaria drug) to standard chemotherapy helps control metastatic colorectal cancer in patients whose tumors show signs of drug resistance. About 155 patients will be screened, with up to 31 receiving the full four-drug combination. Treatment continues until the cancer worsens or side effects become too severe.

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Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G2M9, Canada

  • Sunnybrook Odette Cancer Centre

    Toronto, Ontario, M4N 3M5, Canada

Conditions

Explore the condition pages connected to this study.