New drug duo tested as last hope for spreading colon cancer

NCT ID NCT00826540

Completed Disease control Sponsor: Alliance for Clinical Trials in Oncology Source: ClinicalTrials.gov ↗

Summary

This study tested whether combining two existing cancer drugs—sorafenib and bevacizumab (Avastin)—could help control advanced colorectal cancer that had stopped responding to standard treatments. The trial involved 83 patients whose cancer had spread and progressed despite previous chemotherapy. Researchers measured whether this combination could slow cancer growth for at least three months while monitoring side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Adventist Medical Center

Portland, Oregon, 97216, United States
Allegiance Health

Jackson, Michigan, 49201, United States
Altru Cancer Center

Grand Forks, North Dakota, 58201, United States
Associates In Womens Health

Wichita, Kansas, 67208, United States
Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Bay Area Medical Center

Marinette, Wisconsin, 54143, United States
Berdeaux, Donald MD (UIA Investigator)

Great Falls, Montana, 59405, United States
Billings Clinic

Billings, Montana, 59107-7000, United States
Bismarck Cancer Center

Bismarck, North Dakota, 58501, United States
Bixby Medical Center

Adrian, Michigan, 49221, United States
Blanchard Valley Hospital

Findlay, Ohio, 45840, United States
Boulder Community Hospital

Boulder, Colorado, 80301, United States
Bozeman Deaconess Cancer Center

Bozeman, Montana, 59715, United States
Bromenn Regional Medical Center

Normal, Illinois, 61761, United States
Cancer Center of Kansas - Chanute

Chanute, Kansas, 66720, United States
Cancer Center of Kansas - Dodge City

Dodge City, Kansas, 67801, United States
Cancer Center of Kansas - El Dorado

El Dorado, Kansas, 67042, United States
Cancer Center of Kansas - Fort Scott

Fort Scott, Kansas, 66701, United States
Cancer Center of Kansas - Main Office

Wichita, Kansas, 67214, United States
Cancer Center of Kansas - Newton

Newton, Kansas, 67114, United States
Cancer Center of Kansas - Parsons

Parsons, Kansas, 67357, United States
Cancer Center of Kansas - Pratt

Pratt, Kansas, 67124, United States
Cancer Center of Kansas - Salina

Salina, Kansas, 67401, United States
Cancer Center of Kansas - Wellington

Wellington, Kansas, 67152, United States
Cancer Center of Kansas - Winfield

Winfield, Kansas, 67156, United States
Cancer Center of Kansas-Independence

Independence, Kansas, 67301, United States
Cancer Center of Kansas-Kingman

Kingman, Kansas, 67068, United States
Cancer Center of Kansas-Wichita Medical Arts Tower

Wichita, Kansas, 67208, United States
Cedar Rapids Oncology Association

Cedar Rapids, Iowa, 52403, United States
Center for Cancer Care and Research

St Louis, Missouri, 63141, United States
Clinton Memorial Hospital

Wilmington, Ohio, 45177, United States
Colorado Cancer Research Program CCOP

Denver, Colorado, 80224-2522, United States
Community Cancer Center Foundation

Normal, Illinois, 61761, United States
Community Cancer Center of Monroe

Monroe, Michigan, 48162, United States
Community Howard Regional Health

Kokomo, Indiana, 46904, United States
Community Medical Hospital

Missoula, Montana, 59801, United States
Constantinou, Costas L MD (UIA Investigator)

Bettendorf, Iowa, 52722, United States
Dayton CCOP

Dayton, Ohio, 45420, United States
Elkhart General Hospital

Elkhart, Indiana, 46515, United States
Essentia Health Duluth Clinic CCOP

Duluth, Minnesota, 55805, United States
Essentia Health Saint Mary's Medical Center

Duluth, Minnesota, 55805, United States
Eureka Hospital

Eureka, Illinois, 61530, United States
Exempla Lutheran Medical Center

Wheat Ridge, Colorado, 80033, United States
Exempla Saint Joseph Hospital

Denver, Colorado, 80218, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview-Southdale Hospital

Edina, Minnesota, 55435, United States
Flower Hospital

Sylvania, Ohio, 43560, United States
Fredericksburg Oncology Inc

Fredericksburg, Virginia, 22401, United States
Fulton County Health Center

Wauseon, Ohio, 43567, United States
Galesburg Clinic

Galesburg, Illinois, 61401, United States
Galesburg Cottage Hospital

Galesburg, Illinois, 61401, United States
Garneau, Stewart C MD (UIA Investigator)

Moline, Illinois, 61265, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822-2001, United States
Geisinger Medical Center-Cancer Center Hazelton

Hazleton, Pennsylvania, 18201, United States
Geisinger Medical Group

State College, Pennsylvania, 16801, United States
Geisinger Wyoming Valley

Wilkes-Barre, Pennsylvania, 18711, United States
Genesys Regional Medical Center-West Flint Campus

Flint, Michigan, 48532, United States
Glacier Oncology PLLC

Kalispell, Montana, 59901, United States
Good Samaritan Hospital - Dayton

Dayton, Ohio, 45406, United States
Graham Hospital Association

Canton, Illinois, 61520, United States
Grandview Hospital

Dayton, Ohio, 45405, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Green Bay Oncology - Escanaba

Escanaba, Michigan, 49431, United States
Green Bay Oncology - Iron Mountain

Iron Mountain, Michigan, 49801, United States
Green Bay Oncology - Oconto Falls

Oconto Falls, Wisconsin, 54154, United States
Green Bay Oncology - Sturgeon Bay

Sturgeon Bay, Wisconsin, 54235, United States
Green Bay Oncology Limited at Saint Mary's Hospital

Green Bay, Wisconsin, 54303, United States
Green Bay Oncology at Saint Vincent Hospital

Green Bay, Wisconsin, 54301-3526, United States
Greene Memorial Hospital

Xenia, Ohio, 45385, United States
Guardian Oncology and Center for Wellness

Missoula, Montana, 59804, United States
Hematology Oncology Center Incorporated

Elyria, Ohio, 44035, United States
Hematology-Oncology Centers of the Northern Rockies PC

Billings, Montana, 59102, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Hickman Cancer Center

Adrian, Michigan, 49221, United States
Holy Family Medical Center

Monmouth, Illinois, 61462, United States
Holy Family Memorial Hospital

Manitowoc, Wisconsin, 54221, United States
Hospital District Sixth of Harper County

Anthony, Kansas, 67003, United States
Hurley Medical Center

Flint, Michigan, 48502, United States
Hutchinson Area Health Care

Hutchinson, Minnesota, 55350, United States
Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois Oncology Research Association CCOP

Peoria, Illinois, 61615, United States
Illinois Valley Hospital

Peru, Illinois, 61354, United States
Immanuel-Saint Joseph Hospital-Mayo Health System

Mankato, Minnesota, 56002, United States
Indiana University Health La Porte Hospital

La Porte, Indiana, 46350, United States
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Iowa Oncology Research Association CCOP

Des Moines, Iowa, 50309, United States
Kalispell Medical Oncology

Kalispell, Montana, 59901, United States
Kalispell Regional Medical Center

Kalispell, Montana, 59901, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Lakeland Hospital

Saint Joseph, Michigan, 49085, United States
Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States
Lima Memorial Hospital

Lima, Ohio, 45804, United States
Longmont United Hospital

Longmont, Colorado, 80501, United States
Mason District Hospital

Havana, Illinois, 62644, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Mayo Clinic Health System Eau Claire Hospital - Luther Campus

Eau Claire, Wisconsin, 54703, United States
Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
McKee Medical Center

Loveland, Colorado, 80539, United States
Mcdonough District Hospital

Macomb, Illinois, 61455, United States
Medical Oncology and Hematology Associates

Des Moines, Iowa, 50314, United States
Medical Oncology and Hematology Associates-Des Moines

Des Moines, Iowa, 50309, United States
Medical Oncology and Hematology Associates-West Des Moines

Clive, Iowa, 50325, United States
Memorial Hospital

Carthage, Illinois, 62321, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Mercy Cancer Center at Saint Anne Mercy Hospital

Toledo, Ohio, 43623, United States
Mercy Capitol

Des Moines, Iowa, 50307, United States
Mercy Hospital

Cedar Rapids, Iowa, 52403, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy Hospital of Tiffin

Tiffin, Ohio, 44883, United States
Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314, United States
Mercy Medical Center - North Iowa

Mason City, Iowa, 50401, United States
Mercy Medical Center-Sioux City

Sioux City, Iowa, 51104, United States
Mercy Memorial Hospital

Monroe, Michigan, 48162, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61603, United States
Metro-Minnesota CCOP

Saint Louis Park, Minnesota, 55416, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Michigan Cancer Research Consortium Community Clinical Oncology Program

Ann Arbor, Michigan, 48106, United States
Mid Dakota Clinic

Bismarck, North Dakota, 58501, United States
Midelfort Clinic-Clairemont Campus

Eau Claire, Wisconsin, 54702, United States
Miller-Dwan Hospital

Duluth, Minnesota, 55805, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Minnesota Oncology and Hematology PA-Woodbury

Woodbury, Minnesota, 55125, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Montana Cancer Consortium CCOP

Billings, Montana, 59101, United States
Montana Cancer Specialists

Missoula, Montana, 59802, United States
North Coast Cancer Care

Sandusky, Ohio, 44870, United States
North Coast Cancer Care-Clyde

Clyde, Ohio, 43410, United States
North Colorado Medical Center

Greeley, Colorado, 80631, United States
North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States
North Suburban Medical Center

Thornton, Colorado, 80229, United States
Northern Indiana Cancer Research Consortium

South Bend, Indiana, 46601, United States
Northern Montana Hospital

Havre, Montana, 59501, United States
Northern Rockies Radiation Oncology Center

Billings, Montana, 59101, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
Oakwood Hospital

Dearborn, Michigan, 48124, United States
Oncology Associates at Mercy Medical Center

Cedar Rapids, Iowa, 52403, United States
Ottawa Regional Hospital and Healthcare Center

Ottawa, Illinois, 61350, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
Pekin Cancer Treatment Center

Pekin, Illinois, 61554, United States
Pekin Hospital

Pekin, Illinois, 61554, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Perry Memorial Hospital

Princeton, Illinois, 61356, United States
Porter Adventist Hospital

Denver, Colorado, 80210, United States
Porubcin, Michael MD (UIA Investigator)

Moline, Illinois, 61265, United States
Presbyterian - Saint Lukes Medical Center - Health One

Denver, Colorado, 80218, United States
Proctor Hospital

Peoria, Illinois, 61614, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Reid Hospital and Health Care Services

Richmond, Indiana, 47374, United States
Ridgeview Medical Center

Waconia, Minnesota, 55387, United States
Rose Medical Center

Denver, Colorado, 80220, United States
Saint Alexius Medical Center

Bismarck, North Dakota, 58501, United States
Saint Anthony Central Hospital

Denver, Colorado, 80204, United States
Saint Charles Hospital

Oregon, Ohio, 43616, United States
Saint Francis Hospital and Health Centers

Beech Grove, Indiana, 46107, United States
Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint John Hospital and Medical Center

Detroit, Michigan, 48236, United States
Saint John Macomb-Oakland Hospital

Warren, Michigan, 48093, United States
Saint John's Hospital

Springfield, Missouri, 65804, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Saint Joseph Medical Center

Bloomington, Illinois, 61701, United States
Saint Joseph Mercy Hospital

Ann Arbor, Michigan, 48106-0995, United States
Saint Joseph Mercy Oakland

Pontiac, Michigan, 48341-2985, United States
Saint Joseph Mercy Port Huron

Port Huron, Michigan, 48060, United States
Saint Joseph Regional Medical Center-Mishawaka

Mishawaka, Indiana, 46545-1470, United States
Saint Luke's Hospital

Maumee, Ohio, 43537, United States
Saint Luke's Regional Medical Center

Sioux City, Iowa, 51104, United States
Saint Margaret's Hospital

Spring Valley, Illinois, 61362, United States
Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004, United States
Saint Mary Mercy Hospital

Livonia, Michigan, 48154, United States
Saint Mary's Hospital

Green Bay, Wisconsin, 54303, United States
Saint Mary's Hospital and Regional Medical Center

Grand Junction, Colorado, 81502, United States
Saint Mary's of Michigan

Saginaw, Michigan, 48601, United States
Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802, United States
Saint Peter's Community Hospital

Helena, Montana, 59601, United States
Saint Vincent Healthcare

Billings, Montana, 59101, United States
Saint Vincent Hospital

Green Bay, Wisconsin, 54301, United States
Saint Vincent Mercy Medical Center

Toledo, Ohio, 43608, United States
Samaritan North Health Center

Dayton, Ohio, 45415, United States
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Sanford Clinic North-Bemidgi

Bemidji, Minnesota, 56601, United States
Sanford Clinic North-Fargo

Fargo, North Dakota, 58122, United States
Sanford Medical Center-Fargo

Fargo, North Dakota, 58122, United States
Sharis, Christine M MD (UIA Investigator)

Moline, Illinois, 61265, United States
Siouxland Hematology Oncology Associates

Sioux City, Iowa, 51101, United States
Sky Ridge Medical Center

Lone Tree, Colorado, 80124, United States
South Bend Clinic

South Bend, Indiana, 46617, United States
Sparrow Hospital

Lansing, Michigan, 48912, United States
Stoffel, Thomas J MD (UIA Investigator)

Moline, Illinois, 61265, United States
Swedish Medical Center

Englewood, Colorado, 80110, United States
The Medical Center of Aurora

Aurora, Colorado, 80012, United States
The Toledo Hospital/Toledo Children's Hospital

Toledo, Ohio, 43606, United States
Toledo Clinic Cancer Centers-Bowling Green

Bowling Green, Ohio, 43402, United States
Toledo Clinic Cancer Centers-Maumee

Maumee, Ohio, 43537-1839, United States
Toledo Clinic Cancer Centers-Oregon

Oregon, Ohio, 43616, United States
Toledo Clinic Cancer Centers-Toledo

Toledo, Ohio, 43623, United States
Toledo Community Hospital Oncology Program CCOP

Toledo, Ohio, 43617, United States
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center

Maumee, Ohio, 43537, United States
United Hospital

Saint Paul, Minnesota, 55102, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University of Toledo

Toledo, Ohio, 43614, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
Via Christi Regional Medical Center

Wichita, Kansas, 67214, United States
Virginia Piper Cancer Institute

Minneapolis, Minnesota, 55407, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
Wichita CCOP

Wichita, Kansas, 67214, United States

Conditions

Explore the condition pages connected to this study.

RECURRENT COLON CANCER RECURRENT RECTAL CANCER STAGE IV COLON CANCER STAGE IV RECTAL CANCER