New hope for advanced colon cancer patients after standard treatments fail

NCT ID NCT07381764

Summary

This study tests whether reusing a previous drug combination (irinotecan plus cetuximab) works better than the current standard treatment for advanced colorectal cancer that has worsened after two rounds of therapy. Researchers will enroll 150 patients whose cancer has specific genetic markers found through a blood test. Participants will be randomly assigned to receive one of the two treatment combinations to see which leads to better tumor shrinkage and longer survival.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • A.O. 'Pia Fondazione Cardinale G. Panico'

    Tricase, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • A.O.R.N. "Sant'anna e San Sebastiano"

    Caserta, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • A.O.U. Careggi

    Florence, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • A.O.U. Ospedali Riuniti

    Ancona, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • A.O.U. Pisana

    Pisa, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • A.O.U. Sassari

    Sassari, Italy

  • A.O.U. dell'Università degli studi della Campania "Luigi Vanvitelli"

    Naples, Italy

  • A.R.N.A.S. Garibaldi - P.O. Garibaldi-Nesima

    Catania, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AOU Policlinico di Modena

    Modena, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ARNAS Civico - Di Cristina-Benfratelli - P. O. 'Civico e Benfratelli'

    Palermo, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ASST Grande Ospedale Metropolitano Niguarda

    Milan, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ASST Sette Laghi-Ospedale di Circolo Fondazione Macchi

    Varese, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda Ospedaliero Universitaria "SS Antonio e Biagio e Cesare Arrigo"

    Alessandria, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda Ospedaliero-Universitaria Renato Dulbecco

    Catanzaro, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Casa di Cura Villa Maria

    Mirabella Eclano, Italy

  • Casa di cura Macchiarella

    Palermo, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centro di Riferimento Oncologico (CRO), IRCCS

    Aviano, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione IRCCS Istituto Nazionale Tumori

    Milan, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione IRCCS Ospedale Casa Sollievo della Sofferenza

    San Giovanni Rotondo, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS

    Roma, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Istituto Europeo di Oncologia

    Milan, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Istituto Nazionale Tumori 'Fondazione G. Pascale'

    Naples, Italy

  • Istituto Oncologico Veneto IRCCS

    Padua, Italy

  • Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori'

    Meldola, Italy

    Contact Email: •••••@•••••

  • Ospedale IRCCS 'Saverio de Bellis'

    Castellana Grotte, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale San Giuseppe Moscati

    Statte, Italy

Conditions

Explore the condition pages connected to this study.