Can a probiotic keep ulcerative colitis in check?
NCT ID NCT07751081
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial is testing whether a probiotic supplement called Colipral, which contains a specific strain of E. coli bacteria, can improve gut health in people with ulcerative colitis who are in remission but still have digestive issues. Participants will take either the supplement or a placebo for 60 days, then switch, so everyone gets both. The study will look at changes in gut bacteria, markers of inflammation, and symptoms to see if the probiotic helps maintain remission and ease discomfort.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a food supplement containing the probiotic strain Escherichia coli 5C LMG S-33222 (Colipral)
- What this could lead to
- If effective, this probiotic could help maintain remission and ease gut symptoms in people with ulcerative colitis, potentially improving quality of life.
- What could go wrong
- This is a small, early-stage trial, and the supplement may not significantly alter gut bacteria or symptoms. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Azienda Ospedale - Univeristà Padova
Padova, Padova, 35128, Italy
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