Could a simple block test detect 'Silent' brain fog in liver disease?

NCT ID NCT06619106

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a new cognitive test using building blocks to quickly screen for minimal hepatic encephalopathy (MHE), a subtle brain complication in people with liver disease. Researchers will compare the test's accuracy against standard methods in 100 adults with liver fibrosis, cirrhosis, or porto-systemic shunts. If proven reliable, it could offer a faster, simpler way to diagnose MHE.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cognitive test using building blocks
What this could lead to
If successful, this could provide a quick, reliable screening tool for minimal hepatic encephalopathy, helping doctors diagnose it earlier and more accurately.
What could go wrong
This is a small pilot study (100 participants) testing a new tool against existing tests. It may not prove accurate enough or may not work in broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hepato-gastro-enterology department, Pitié Salpêtrière hospital

    RECRUITING

    Paris, 75013, France