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New hope for 'chemo brain': study tests two therapies to sharpen memory in breast cancer survivors

NCT ID NCT05289258

Recruiting now Symptom relief Sponsor: Universidad de Córdoba Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two non-drug treatments—cognitive rehabilitation (brain training) and the Unified Barlow Protocol (emotional therapy)—against a waitlist group to see if they can reduce memory and thinking problems in breast cancer survivors. 123 survivors with mild to moderate cognitive issues will be randomly assigned to one of the three groups. The goal is to improve cognitive function, emotional health, and quality of life, with results checked after six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cognitive rehabilitation and Unified Barlow Protocol (behavioral interventions)
What this could lead to
If successful, this could offer breast cancer survivors a non-drug way to improve memory, thinking, and emotional well-being after chemotherapy.
What could go wrong
This is a small, early-stage trial with 123 participants. The interventions are behavioral, so results may vary and may not apply to all survivors. Long-term benefits are uncertain.

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Conditions

The condition(s) this trial relates to.

anxiety disorder breast cancer breast carcinoma breast neoplasm Cognitive Dysfunction Depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER, BREAST

Contacts and locations

Locations

  • Hospital Universitario Reina Sofía

    NOT_YET_RECRUITING

    Córdoba, 14005, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Reina Sofía University Hospital

    RECRUITING

    Córdoba, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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