Computer exercises may retrain the brain to fight depression

NCT ID NCT01454141

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether a computer-based program called cognitive control training (CCT) can help people with depression feel less negative mood and rumination. Participants with high depression scores complete three sessions of CCT or a comparison task over two weeks. The goal is to see if strengthening attention and executive control through repeated exercises can improve emotional well-being.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
computer-based cognitive control training
What this could lead to
If effective, this approach could offer a non-drug, brain-training method to help people with depression manage negative thoughts and improve mood.
What could go wrong
This is a small, early-stage study with only three sessions of training over two weeks, so any benefits may be short-lived or not apply to everyone with depression.

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Conditions

The condition(s) this trial relates to.

Consciousness Disorders Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston University

    Boston, Massachusetts, 02215, United States

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