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Blood gas clues: could CO2 markers forecast heart trouble in young surgery patients?

NCT ID NCT07770386

Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 18, 2026 · Last updated Sep 09, 2026 · Updated 2 times

Summary

This study looks at whether certain carbon dioxide (CO2) measurements in the blood can help predict a serious complication called low cardiac output syndrome (LCOS) in children after heart surgery. LCOS happens when the heart doesn't pump enough blood, which can lead to longer hospital stays and other problems. The researchers will measure CO2-related values in children under 18 who had heart surgery with a heart-lung machine and are in the intensive care unit. The goal is to see if these simple blood tests can warn doctors early about heart issues, so they can act faster.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better early detection of dangerous drops in heart function after pediatric heart surgery, potentially improving recovery and reducing complications.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The markers may not be accurate enough in children, and results may not apply to all surgical settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 306 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jul 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children after cardiac surgery with cardiopulmonary bypass (CPB)

Ages

Up to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children under the age of 18 * Post-operative cardiac surgery * Surgery with extracorporeal circulation * With a central venous catheter and an arterial catheter * Admitted to the pediatric intensive care unit at Lille University Hospital * Patient covered by the social security system (or equivalent) Exclusion Criteria: * Pre-existing renal insufficiency prior to cardiac surgery * Opposition from the holder of parental authority * Difficulty understanding or communicating, making it impossible to inform the holder of parental authority * Patient under legal protection (guardianship, curatorship, legal safeguard) * Malposition of the central venous catheter * Malposition of the arterial catheter * Biological samples that cannot be interpreted

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Conditions

The condition(s) this trial relates to.

Cardiac Output, Low postoperative ventricular dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Low cardiac output syndrome bypass children

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU Lille

    RECRUITING

    Lille, France