Scientists test if carbon dioxide flushes brain waste

NCT ID NCT07357090

Recruiting now Knowledge-focused Sponsor: Andrew Mayer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether breathing slightly higher levels of carbon dioxide (CO2) can safely increase the movement of proteins from the brain into the blood, which may indicate better waste clearance. Researchers will compare healthy adults and those with a history of traumatic brain injury (TBI), using MRI scans and blood tests. The goal is to understand how CO2 affects brain cleaning processes, not to treat any condition directly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: carbon dioxide (CO2) gas mixture
What this could lead to: If it works, this could point toward a new way to help the brain clear waste, potentially aiding recovery after brain injury.
What could go wrong: This is an early, small study focused on measuring effects, not treatment. It may not show clear benefits or translate into a therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AGING DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic premature aging syndrome traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING DISORDER MAGNETIC RESONANCE IMAGING (MRI) TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

The Mind Research Network
RECRUITING

Albuquerque, New Mexico, 87106, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.