New mRNA vaccine shows promise against common virus in early trial

NCT ID NCT04232280

First seen May 16, 2026 · Last updated Jun 18, 2026 · Updated 5 times

Summary

This study tested an experimental mRNA vaccine (mRNA-1647) for cytomegalovirus (CMV) in 315 healthy adults aged 18-40. The goal was to check safety and see how well the vaccine triggers the immune system to produce antibodies against CMV. Participants received one of three doses or a placebo, and researchers measured side effects and antibody levels in the blood.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alliance for Multispecialty Research

    Lexington, Kentucky, 40509, United States

  • Aventiv Research Inc

    Columbus, Ohio, 43213-6523, United States

  • Benchmark Research

    Sacramento, California, 95864, United States

  • Crossroads Clinical Research

    Victoria, Texas, 77901, United States

  • Foothill Family Clinic

    Salt Lake City, Utah, 84109, United States

  • Foothill Family Clinic-South Clinic

    Salt Lake City, Utah, 84121, United States

  • Johnson County Clin-Trials

    Lenexa, Kansas, 66219, United States

  • Optimal Research

    Peoria, Illinois, 61614, United States

  • Tekton Research Inc

    Austin, Texas, 78745, United States

Conditions

The condition(s) this trial relates to.

DNA Virus Infections viral infectious disease cytomegalovirus infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.