New strategy aims to tame dangerous virus after cancer transplant
NCT ID NCT01199562
Summary
This study is testing a personalized plan to manage cytomegalovirus (CMV), a common and potentially serious infection, in patients who have received a donor stem cell transplant for blood cancers or disorders. The plan involves closely monitoring the virus level and the patient's immune status to decide when to start and stop antiviral drugs. Researchers also want to understand how the patient's and donor's genetics affect the risk of the virus coming back.
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Contacts and locations
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
Conditions
Explore the condition pages connected to this study.
ACCELERATED PHASE CHRONIC MYELOGENOUS LEUKEMIA
ACUTE UNDIFFERENTIATED LEUKEMIA
ADULT ACUTE LYMPHOBLASTIC LEUKEMIA IN REMISSION
ADULT ACUTE MYELOID LEUKEMIA IN REMISSION
ADULT ACUTE MYELOID LEUKEMIA WITH 11Q23 (MLL) ABNORMALITIES
ADULT ACUTE MYELOID LEUKEMIA WITH DEL(5Q)
ADULT ACUTE MYELOID LEUKEMIA WITH INV(16)(P13;Q22)
ADULT ACUTE MYELOID LEUKEMIA WITH T(15;17)(Q22;Q12)
ADULT ACUTE MYELOID LEUKEMIA WITH T(16;16)(P13;Q22)
ADULT ACUTE MYELOID LEUKEMIA WITH T(8;21)(Q22;Q22)
ADULT GRADE III LYMPHOMATOID GRANULOMATOSIS
ADULT NASAL TYPE EXTRANODAL NK/T-CELL LYMPHOMA
ANAPLASTIC LARGE CELL LYMPHOMA
ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA
APLASTIC ANEMIA
ATYPICAL CHRONIC MYELOID LEUKEMIA, BCR-ABL NEGATIVE
BLASTIC PHASE CHRONIC MYELOGENOUS LEUKEMIA
CHRONIC EOSINOPHILIC LEUKEMIA
CHRONIC MYELOMONOCYTIC LEUKEMIA
CHRONIC NEUTROPHILIC LEUKEMIA
CHRONIC PHASE CHRONIC MYELOGENOUS LEUKEMIA
CONTIGUOUS STAGE II ADULT BURKITT LYMPHOMA
CONTIGUOUS STAGE II ADULT DIFFUSE LARGE CELL LYMPHOMA
CONTIGUOUS STAGE II ADULT DIFFUSE MIXED CELL LYMPHOMA
CONTIGUOUS STAGE II ADULT DIFFUSE SMALL CLEAVED CELL LYMPHOMA
CONTIGUOUS STAGE II ADULT IMMUNOBLASTIC LARGE CELL LYMPHOMA
CONTIGUOUS STAGE II ADULT LYMPHOBLASTIC LYMPHOMA
CONTIGUOUS STAGE II GRADE 1 FOLLICULAR LYMPHOMA
CONTIGUOUS STAGE II GRADE 2 FOLLICULAR LYMPHOMA
CONTIGUOUS STAGE II GRADE 3 FOLLICULAR LYMPHOMA
CONTIGUOUS STAGE II MANTLE CELL LYMPHOMA
CONTIGUOUS STAGE II MARGINAL ZONE LYMPHOMA
CONTIGUOUS STAGE II SMALL LYMPHOCYTIC LYMPHOMA
CUTANEOUS B-CELL NON-HODGKIN LYMPHOMA
CYTOMEGALOVIRUS INFECTION
DE NOVO MYELODYSPLASTIC SYNDROMES
ESSENTIAL THROMBOCYTHEMIA
EXTRAMEDULLARY PLASMACYTOMA
EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE
HEMATOPOIETIC/LYMPHOID CANCER
INTRAOCULAR LYMPHOMA
ISOLATED PLASMACYTOMA OF BONE
MAST CELL LEUKEMIA
MENINGEAL CHRONIC MYELOGENOUS LEUKEMIA
MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM, UNCLASSIFIABLE
NODAL MARGINAL ZONE B-CELL LYMPHOMA
NONCONTIGUOUS STAGE II ADULT BURKITT LYMPHOMA
NONCONTIGUOUS STAGE II ADULT DIFFUSE LARGE CELL LYMPHOMA
NONCONTIGUOUS STAGE II ADULT DIFFUSE MIXED CELL LYMPHOMA
NONCONTIGUOUS STAGE II ADULT DIFFUSE SMALL CLEAVED CELL LYMPHOMA
NONCONTIGUOUS STAGE II ADULT IMMUNOBLASTIC LARGE CELL LYMPHOMA
NONCONTIGUOUS STAGE II ADULT LYMPHOBLASTIC LYMPHOMA
NONCONTIGUOUS STAGE II GRADE 1 FOLLICULAR LYMPHOMA
NONCONTIGUOUS STAGE II GRADE 2 FOLLICULAR LYMPHOMA
NONCONTIGUOUS STAGE II GRADE 3 FOLLICULAR LYMPHOMA
NONCONTIGUOUS STAGE II MANTLE CELL LYMPHOMA
NONCONTIGUOUS STAGE II MARGINAL ZONE LYMPHOMA
NONCONTIGUOUS STAGE II SMALL LYMPHOCYTIC LYMPHOMA
POLYCYTHEMIA VERA
POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER
PREVIOUSLY TREATED MYELODYSPLASTIC SYNDROMES
PRIMARY MYELOFIBROSIS
PRIMARY SYSTEMIC AMYLOIDOSIS
PROGRESSIVE HAIRY CELL LEUKEMIA, INITIAL TREATMENT
PROLYMPHOCYTIC LEUKEMIA
RECURRENT ADULT ACUTE LYMPHOBLASTIC LEUKEMIA
RECURRENT ADULT ACUTE MYELOID LEUKEMIA
RECURRENT ADULT BURKITT LYMPHOMA
RECURRENT ADULT DIFFUSE LARGE CELL LYMPHOMA
RECURRENT ADULT DIFFUSE MIXED CELL LYMPHOMA
RECURRENT ADULT DIFFUSE SMALL CLEAVED CELL LYMPHOMA
RECURRENT ADULT GRADE III LYMPHOMATOID GRANULOMATOSIS
RECURRENT ADULT HODGKIN LYMPHOMA
RECURRENT ADULT IMMUNOBLASTIC LARGE CELL LYMPHOMA
RECURRENT ADULT LYMPHOBLASTIC LYMPHOMA
RECURRENT ADULT T-CELL LEUKEMIA/LYMPHOMA
RECURRENT CUTANEOUS T-CELL NON-HODGKIN LYMPHOMA
RECURRENT GRADE 1 FOLLICULAR LYMPHOMA
RECURRENT GRADE 2 FOLLICULAR LYMPHOMA
RECURRENT GRADE 3 FOLLICULAR LYMPHOMA
RECURRENT MANTLE CELL LYMPHOMA
RECURRENT MARGINAL ZONE LYMPHOMA
RECURRENT MYCOSIS FUNGOIDES/SEZARY SYNDROME
RECURRENT SMALL LYMPHOCYTIC LYMPHOMA
REFRACTORY CHRONIC LYMPHOCYTIC LEUKEMIA
REFRACTORY HAIRY CELL LEUKEMIA
REFRACTORY MULTIPLE MYELOMA
RELAPSING CHRONIC MYELOGENOUS LEUKEMIA
SECONDARY ACUTE MYELOID LEUKEMIA
SECONDARY MYELODYSPLASTIC SYNDROMES
SECONDARY MYELOFIBROSIS
SPLENIC MARGINAL ZONE LYMPHOMA
STAGE 0 CHRONIC LYMPHOCYTIC LEUKEMIA
STAGE I ADULT BURKITT LYMPHOMA
STAGE I ADULT DIFFUSE LARGE CELL LYMPHOMA
STAGE I ADULT DIFFUSE MIXED CELL LYMPHOMA
STAGE I ADULT DIFFUSE SMALL CLEAVED CELL LYMPHOMA
STAGE I ADULT HODGKIN LYMPHOMA
STAGE I ADULT IMMUNOBLASTIC LARGE CELL LYMPHOMA
STAGE I ADULT LYMPHOBLASTIC LYMPHOMA
STAGE I ADULT T-CELL LEUKEMIA/LYMPHOMA
STAGE I CHRONIC LYMPHOCYTIC LEUKEMIA
STAGE I CUTANEOUS T-CELL NON-HODGKIN LYMPHOMA
STAGE I GRADE 1 FOLLICULAR LYMPHOMA
STAGE I GRADE 2 FOLLICULAR LYMPHOMA
STAGE I GRADE 3 FOLLICULAR LYMPHOMA
STAGE I MANTLE CELL LYMPHOMA
STAGE I MARGINAL ZONE LYMPHOMA
STAGE I MULTIPLE MYELOMA
STAGE I MYCOSIS FUNGOIDES/SEZARY SYNDROME
STAGE I SMALL LYMPHOCYTIC LYMPHOMA
STAGE II ADULT HODGKIN LYMPHOMA
STAGE II ADULT T-CELL LEUKEMIA/LYMPHOMA
STAGE II CHRONIC LYMPHOCYTIC LEUKEMIA
STAGE II CUTANEOUS T-CELL NON-HODGKIN LYMPHOMA
STAGE II MULTIPLE MYELOMA
STAGE II MYCOSIS FUNGOIDES/SEZARY SYNDROME
STAGE III ADULT BURKITT LYMPHOMA
STAGE III ADULT DIFFUSE LARGE CELL LYMPHOMA
STAGE III ADULT DIFFUSE MIXED CELL LYMPHOMA
STAGE III ADULT DIFFUSE SMALL CLEAVED CELL LYMPHOMA
STAGE III ADULT HODGKIN LYMPHOMA
STAGE III ADULT IMMUNOBLASTIC LARGE CELL LYMPHOMA
STAGE III ADULT LYMPHOBLASTIC LYMPHOMA
STAGE III ADULT T-CELL LEUKEMIA/LYMPHOMA
STAGE III CHRONIC LYMPHOCYTIC LEUKEMIA
STAGE III CUTANEOUS T-CELL NON-HODGKIN LYMPHOMA
STAGE III GRADE 1 FOLLICULAR LYMPHOMA
STAGE III GRADE 2 FOLLICULAR LYMPHOMA
STAGE III GRADE 3 FOLLICULAR LYMPHOMA
STAGE III MANTLE CELL LYMPHOMA
STAGE III MARGINAL ZONE LYMPHOMA
STAGE III MULTIPLE MYELOMA
STAGE III MYCOSIS FUNGOIDES/SEZARY SYNDROME
STAGE III SMALL LYMPHOCYTIC LYMPHOMA
STAGE IV ADULT BURKITT LYMPHOMA
STAGE IV ADULT DIFFUSE LARGE CELL LYMPHOMA
STAGE IV ADULT DIFFUSE MIXED CELL LYMPHOMA
STAGE IV ADULT DIFFUSE SMALL CLEAVED CELL LYMPHOMA
STAGE IV ADULT HODGKIN LYMPHOMA
STAGE IV ADULT IMMUNOBLASTIC LARGE CELL LYMPHOMA
STAGE IV ADULT LYMPHOBLASTIC LYMPHOMA
STAGE IV ADULT T-CELL LEUKEMIA/LYMPHOMA
STAGE IV CHRONIC LYMPHOCYTIC LEUKEMIA
STAGE IV CUTANEOUS T-CELL NON-HODGKIN LYMPHOMA
STAGE IV GRADE 1 FOLLICULAR LYMPHOMA
STAGE IV GRADE 2 FOLLICULAR LYMPHOMA
STAGE IV GRADE 3 FOLLICULAR LYMPHOMA
STAGE IV MANTLE CELL LYMPHOMA
STAGE IV MARGINAL ZONE LYMPHOMA
STAGE IV MYCOSIS FUNGOIDES/SEZARY SYNDROME
STAGE IV SMALL LYMPHOCYTIC LYMPHOMA
T-CELL LARGE GRANULAR LYMPHOCYTE LEUKEMIA
WALDENSTROM MACROGLOBULINEMIA