Custom gene-targeting drug tested in single patient with rare nerve disease

NCT ID NCT07223632

First seen Nov 03, 2025 · Last updated May 13, 2026 · Updated 29 times

Summary

This study tests a custom-made drug (VCA-894A) in one person with a specific genetic form of Charcot-Marie-Tooth disease (CMT2S). The drug is designed to fix a genetic error and restore a missing protein. It is given via spinal injection to see if it is safe and can improve muscle function.

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Contacts and locations

Locations

  • Vanda Investigational Site

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.