Could a psychoactive compound curb alcohol cravings? new trial launches

NCT ID NCT05913752

Recruiting now Disease control Sponsor: Clearmind Medicine Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new drug called CMND-100 (MEAI) in healthy volunteers and people with alcohol use disorder. The goal is to find a safe dose and see if it can reduce drinking and cravings. The trial is currently recruiting 84 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CMND-100 (MEAI), a psychoactive compound of the aminoindane class
What this could lead to: If successful, this could point toward a new treatment option to help people with alcohol use disorder reduce their drinking and cravings.
What could go wrong: This is an early phase 1/2 trial with only 84 participants, so it is primarily testing safety and dosing. It may not show clear benefits, and the psychoactive effects of MEAI could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALCOHOL USE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER

Contacts and locations

Show contact details

Locations

Connecticut Mental Health Center
RECRUITING

New Haven, Connecticut, 06519, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hadassah Medical Center
RECRUITING

Jerusalem, 91120, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Johns Hopkins Bayview Medical Center
RECRUITING

Baltimore, Maryland, 21224, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Tel-Aviv Sourasky Medical Center (TASMC)
RECRUITING

Tel Aviv, 6423906, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.