New leukemia treatment strategy aims for a 'Drug Holiday'
NCT ID NCT04070443
Summary
This study is testing a two-step treatment plan for adults newly diagnosed with a common type of chronic leukemia. First, patients take a stronger drug (ponatinib) for six months to deeply reduce the cancer. Then, they switch to a standard, gentler drug (imatinib) for up to three years. The main goal is to see if this approach allows enough patients to reach a point where they can safely stop all medication for a period of time.
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Contacts and locations
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Locations
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CH d'Avignon
Avignon, 84000, France
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CH de Versailles - Hôpital André Mignot
Le Chesnay, France
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CHRU Nancy/Brabois
Vandœuvre-lès-Nancy, 54500, France
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CHU Limoges - Hôpital Dupuytren
Limoges, France
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CHU Nîmes Caremeau - Institut de Cancérologie du Gard
Nîmes, France
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CHU Strasbourg
Strasbourg, 67000, France
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CHU d'Angers
Angers, France
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CHU de Grenoble
Grenoble, 38000, France
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Centre Hospitalier Annecy-Genevois
Annecy, 74000, France
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Centre Hospitalier Sud Francilien
Corbeil-Essonnes, 91000, France
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Centre Léon Bérard
Lyon, 69008, France
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Chru Besançon
Besançon, 25000, France
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Chru Brest
Brest, France
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Chu - Hopital de Pontchaillou
Rennes, 35000, France
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Chu Amiens Picardie
Amiens, 80000, France
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Chu D'Estaing
Clermont-Ferrand, 63000, France
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Chu Hotel Dieu
Nantes, 44000, France
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Chu Poitiers
Poitiers, France
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Hopital Henri Mondor
Créteil, 94000, France
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Hopital Paul Brousse
Villejuif, 94800, France
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Hopital Saint Eloi
Montpellier, 34000, France
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Hopital Saintantoine
Paris, 75000, France
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Hôpital Claude Huriez - CHRU de Lille
Lille, France
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Institut Bergonie
Bordeaux, 33000, France
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Institut D'Hematologie de Basse Normandie
Caen, 14000, France
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Institut Paoli Calmettes
Marseille, 13000, France
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Institut de Cancérologie Lucien Neuwirth
Saint-Priest-en-Jarez, France
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Iuct Toulouse - Oncopole
Toulouse, France
Conditions
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