New combo therapy may let CML patients pause treatment again
NCT ID NCT03610971
First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 30 times
Summary
This study tests whether adding ruxolitinib to standard tyrosine kinase inhibitor (TKI) therapy helps people with chronic myeloid leukemia (CML) stay in remission after stopping their medication. It includes 24 adults who previously tried and failed to stop TKI therapy. Participants receive the combination for 12 cycles, then attempt to stop all treatment, with the goal of achieving long-term drug-free remission.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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David H. Koch Center for Cancer Care at Memorial Sloan Kettering
New York, New York, 10021, United States
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Duke University Hospital
Durham, North Carolina, 27710, United States
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Emory -Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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Froedtert Hospital & the Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612, United States
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Memorial Sloan Kettering - Bergen
Montvale, New Jersey, 07645, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Roswell Park Comprehensive Cancer Center
Buffalo, New York, 14263, United States
Conditions
Explore the condition pages connected to this study.