Massive CML registry launches to reveal how TKIs really perform
NCT ID NCT07091019
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This registry will follow 1,000 adults with chronic-phase CML who are taking approved TKIs (like Gleevec or Tasigna) as their first or second treatment. Over 5 years, researchers will track side effects, treatment changes, and patient-reported experiences to understand how these drugs work in real-world settings, not just in clinical trials.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tyrosine kinase inhibitors (TKIs) such as asciminib, bosutinib, dasatinib, imatinib, nilotinib
What this could lead to
If successful, this registry could provide clearer insights into how well different TKIs work and are tolerated in everyday medical practice, helping doctors and patients make more informed treatment decisions.
What could go wrong
This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may be influenced by differences in patient care and reporting.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Avera Cancer
RECRUITINGSioux Falls, South Dakota, 57105, United States
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Baylor Scott and White Research
RECRUITINGTemple, Texas, 76502, United States
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Fred Hutchinson Cancer Research Center
RECRUITINGSeattle, Washington, 98109-1024, United States
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Lundquist Inst BioMed at Harbor
RECRUITINGTorrance, California, 90509-2910, United States
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MultiCare Health System Institute
RECRUITINGTacoma, Washington, 98405, United States
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NY Cancer and Blood Specialists
RECRUITINGEast Setauket, New York, 11733, United States
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Northwest Medical Specialties
RECRUITINGTacoma, Washington, 98405, United States
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Oregon Oncology Specialists Salem
RECRUITINGSalem, Oregon, 97301, United States
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SUNY Upstate Medical University
RECRUITINGSyracuse, New York, 13210, United States
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Sacred Heart Medical Oncology
RECRUITINGPensacola, Florida, 32504, United States
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St Agnes Hospital
RECRUITINGBaltimore, Maryland, 21229, United States
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Stamford Hospital
RECRUITINGStamford, Connecticut, 06902, United States
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Stockton Hematology Oncology Medical Group Inc
RECRUITINGStockton, California, 95204, United States
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Tri-County Hematology and Oncology Associates
RECRUITINGCanton, Ohio, 44718, United States
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233-0271, United States
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