Artificial pancreas trial aims to simplify diabetes management

NCT ID NCT06579404

Recruiting now Disease control Sponsor: University of Cambridge Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a fully closed-loop insulin delivery system (an "artificial pancreas") can better control blood sugar in adults with type 2 diabetes who use insulin, compared to their usual insulin therapy with a continuous glucose monitor. About 224 participants will use either the automated system or standard care for 26 weeks. The goal is to see if the closed-loop system improves HbA1c levels and keeps glucose in a healthy range without increasing dangerous low blood sugar episodes.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES TREATED WITH INSULIN

Contacts and locations

Locations

Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust
RECRUITING

Cambridge, United Kingdom
Bern University Hospital
NOT_YET_RECRUITING

Bern, Switzerland
CHU de Toulouse
NOT_YET_RECRUITING

Toulouse, France
Diabetes Centre, Institute of Clinical and Experimental Medicine
NOT_YET_RECRUITING

Prague, Czechia
Guy's and St Thomas' NHS Foundation Trust
RECRUITING

London, United Kingdom
King's College Hospital, King's College NHS Foundation Trust
RECRUITING

London, United Kingdom
Leicester Diabetes Centre
RECRUITING

Leicester, United Kingdom
Manchester Royal Infirmary, Central Manchester University Hospitals NHS Foundation Trust
NOT_YET_RECRUITING

Manchester, United Kingdom
Medical University of Graz
NOT_YET_RECRUITING

Graz, Austria
Norfolk and Norwich University Hospital
RECRUITING

Norwich, United Kingdom
Royal Derby Hospital
NOT_YET_RECRUITING

Derby, United Kingdom
University of Melbourne
NOT_YET_RECRUITING

Melbourne, Australia

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