Chemo drug tested for rare immune disorder that Won't go away
NCT ID NCT02425904
Summary
This study is testing whether a chemotherapy drug called clofarabine can help control Langerhans cell histiocytosis (LCH) and related disorders when they have come back or not responded to previous treatments. It is enrolling 25 participants of all ages who have active disease and have failed at least one prior therapy. The main goal is to see if the drug causes the disease to shrink or go away, while also monitoring side effects and survival.
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Contacts and locations
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Locations
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Arkansas Children's Hospital
Little Rock, Arkansas, 72202, United States
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mount Sinai Medical Center
New York, New York, 10029, United States
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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The Children's Hospital of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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The Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
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University of California San Francisco Medical Center
San Francisco, California, 94143, United States
Conditions
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