Experimental cell therapy targets stubborn leukemia in early trial

NCT ID NCT05654779

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a new treatment called LCAR-AMDR cells in 4 people with acute myeloid leukemia that had come back or not responded to standard therapy. The treatment uses specially engineered immune cells to target two proteins (CLL1 and CD33) on leukemia cells. The main goals were to check safety and find the right dose. The study was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Gobroad BoRen Hospital

    Beijing, Beijing Municipality, 100070, China

  • Chinese Academy of Medical Science and Blood Disease Hospital

    Tianjin, Tianjin Municipality, 300020, China

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