Tailored CLL treatment aims to reduce side effects by skipping unnecessary drugs

This study is testing a new, personalized approach for adults with untreated CLL. The goal is to see if starting with just two oral drugs is effective, and only adding a third drug (an infusion) for patients who still have detectable cancer after the first phase of treatment. This strategy aims to reduce side effects by avoiding unnecessary treatment while trying to achieve the best possible response. The study will enroll 50 participants to measure how well this approach works.