New combo therapy shows promise for First-Line CLL treatment

NCT ID NCT03609593

First seen Feb 28, 2026 · Last updated May 21, 2026 · Updated 9 times

Summary

This study tested a two-step treatment for people with untreated chronic lymphocytic leukemia (CLL). First, participants received a standard chemo-immunotherapy combination (bendamustine and rituximab), followed by a year of the oral targeted drug venetoclax. The goal was to see how many patients had their cancer shrink significantly. The study included 42 adults with CLL who had not had prior therapy.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center / NewYork-Presbyterian Hospital

    New York, New York, 10032, United States

Conditions

Explore the condition pages connected to this study.