New drug duo aims to wipe out cancer cells in returning blood cancers

NCT ID NCT05168930

Summary

This study is testing whether combining two targeted drugs, zanubrutinib and venetoclax, can effectively treat adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has returned after prior therapy. The goal is to see if this combination can achieve deep remissions by making cancer cells undetectable in the blood and bone marrow. The trial will enroll up to 45 participants who will receive treatment for about 15 months, with options for re-treatment if the cancer comes back.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact

  • New England Cancer Specialists

    RECRUITING

    Scarborough, Maine, 04074, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • South Shore Hospital

    RECRUITING

    South Weymouth, Massachusetts, 02190, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.