New hope for Tough-to-Treat blood cancers in major trial

NCT ID NCT06943872

Recruiting now Disease control Sponsor: BeOne Medicines Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new drug called sonrotoclax works better than the current standard treatment, venetoclax, for adults whose chronic lymphocytic leukemia or small lymphocytic lymphoma has returned or stopped responding to previous therapies. About 630 participants will receive either the new combination or the standard one to see which keeps the cancer in check longer and with fewer side effects. The main goal is to see if patients on the new treatment live longer without their cancer getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Affiliated Hospital of Jiangnan University South Campus
RECRUITING

Wuxi, Jiangsu, 214122, China
Affiliated Zhongshan Hospital of Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200032, China
Albert Schweitzer Ziekenhuis
RECRUITING

Dordrecht, 3318 AT, Netherlands
Ao Brotzu Ospedale Oncologico Armando Businco
RECRUITING

Cagliari, 09121, Italy
Arthur Je Child Comprehensive Cancer Centre
RECRUITING

Calgary, Alberta, T2N 5G2, Canada
Asl Salerno Andrea Tortora
RECRUITING

Pagani, 84014, Italy
Atrium Health Wake Forest Baptist
RECRUITING

Winston-Salem, North Carolina, 27157, United States
Auckland City Hospital
RECRUITING

Auckland, 1023, New Zealand
Blacktown Cancer and Haematology Centre
RECRUITING

Blacktown, New South Wales, NSW 2148, Australia
CETUS
ACTIVE_NOT_RECRUITING

Belo Horizonte, 30110-022, Brazil
Centre Henri Becquerel
RECRUITING

Rouen, 76038, France
Centre Hospitalier Universitaire Nantes Hotel Dieu
RECRUITING

Nantes, 44000, France
Chao Family Comprehensive Cancer Center
RECRUITING

Orange, California, 92868-3201, United States
China Japan Friendship Hospital
RECRUITING

Beijing, Beijing Municipality, 100029, China
Chu Clermont Ferrand Therapie Cellulaire and Hematolo
RECRUITING

Clermontferrand, 63100, France
Chu Hopital Lyon Sud
RECRUITING

PierreBenite, 69495, France
Chu Nancy Hopital Brabois
RECRUITING

VandoeuvrelesNancy, 54511, France
Chu Rennes
RECRUITING

Rennes Cedes, 35000, France
Clatterbridge Cancer Centre
RECRUITING

Metropolitan Borough of Wirral, CH63 4JY, United Kingdom
Clinical Research Alliance, Inc
RECRUITING

Westbury, New York, 11590-5119, United States
Cliniques Universitaires Saint Luc
RECRUITING

Brussels, 1200, Belgium
Complexo Hospitalar de Niteroi
ACTIVE_NOT_RECRUITING

Niterói, 24020-096, Brazil
Costa Del Sol (Marbella, Malaga)
RECRUITING

Marbella, 29603, Spain
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215-5418, United States
Dietrich Bonhoeffer Klinikum Neubrandenburg
RECRUITING

Neubrandenburg, 17036, Germany
Eastern Connecticut Hematology and Oncology
RECRUITING

Norwich, Connecticut, 06360-2700, United States
FUNDALEU
RECRUITING

Caba, CP1114, Argentina
Fakultni Nemocnice Brno
RECRUITING

Brno, 625 00, Czechia
Fakultni Nemocnice Hradec Kralove
RECRUITING

Hradec Králové, 500 03, Czechia
Flevoziekenhuis
RECRUITING

Almere Stad, 1315 RA, Netherlands
Freeman Hospital
RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom
Fujian Medical University Union Hospitalqishan Branch
RECRUITING

Fuzhou, Fujian, 350108, China
Fujian Provincial Hospital
RECRUITING

Fuzhou, Fujian, 350001, China
Genesiscare North Shore
RECRUITING

St Leonards, New South Wales, NSW 2065, Australia
Gokos Gmbh
RECRUITING

Dresden, 01307, Germany
Guangxi Medical University Cancer Hospital Wuxiang Branch
RECRUITING

Nanning, Guangxi, 530201, China
Guangzhou First Peoples Hospital
RECRUITING

Guangzhou, Guangdong, 510013, China
Haematologisch Onkologische Schwerpunktpraxis
RECRUITING

Würzburg, 97080, Germany
Hanusch Krankenhaus
RECRUITING

Vienna, 1140, Austria
Hcfmusp Servico de Hematologia, Hemoterapia E Terapia Celular
ACTIVE_NOT_RECRUITING

São Paulo, 05402-000, Brazil
Hopital Robert Debre
RECRUITING

Reims, 51100, France
Hopital de La Pitie Salpetriere
RECRUITING

Paris, 75013, France
Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Erasto Gaertner
ACTIVE_NOT_RECRUITING

Curitiba, 81520-060, Brazil
Hospital Nove de Julho Dasa
ACTIVE_NOT_RECRUITING

São Paulo, 01409-001, Brazil
Hospital Samaritano Sao Paulo
ACTIVE_NOT_RECRUITING

São Paulo, 01232-010, Brazil
Hospital Santa Izabel
ACTIVE_NOT_RECRUITING

Salvador, 40050-410, Brazil
Hospital Santa Rita de Cassia Afecc
ACTIVE_NOT_RECRUITING

Vitória, 29043-260, Brazil
Hospital Sao Lucas
ACTIVE_NOT_RECRUITING

Rio de Janeiro, 22061-080, Brazil
Hospital Universitario Infanta Leonor
RECRUITING

Madrid, 28031, Spain
Hospital Universitario Marques de Valdecilla
RECRUITING

Santander, 39008, Spain
Hospital Universitario de Salamanca
RECRUITING

Salamanca, 37007, Spain
Hospital Virgen de Valme (Sevilla)
RECRUITING

Seville, 41014, Spain
Hospital de La Princesa
RECRUITING

Madrid, 28006, Spain
Ico Lhospitalet Hospital Duran I Reynals
RECRUITING

Lhospitalet de Llobregat, 08908, Spain
Illinois Cancer Specialists (Niles) Usor
RECRUITING

Niles, Illinois, 60714-5905, United States
Instituto Brasileiro de Controle Do Cancer
ACTIVE_NOT_RECRUITING

São Paulo, 04014-002, Brazil
Instituto Dor de Pesquisa E Ensino Rio de Janeiro
ACTIVE_NOT_RECRUITING

Rio de Janeiro, 22281-100, Brazil
Instituto Dor de Pesquisa E Ensino Sao Paulo
ACTIVE_NOT_RECRUITING

São Paulo, 04501-000, Brazil
Irmandade Da Santa Casa de Misericordia Hospital Porto Alegre
ACTIVE_NOT_RECRUITING

Porto Alegre, 90020-090, Brazil
Iuct Oncopole
RECRUITING

Toulouse, 31100, France
Jiangxi Cancer Hospital
RECRUITING

Nanchang, Jiangxi, 330029, China
Jining No1 Peoples Hospital West Branch
RECRUITING

Jining, Shandong, 272000, China
Karolinska Universitetssjukhuset Solna
RECRUITING

Stockholm, 171 76, Sweden
Kings College Hospital
RECRUITING

London, SE5 9RS, United Kingdom
Klinikum Der Universitat Munchen Medizinische Klinik Und Poliklinik Iii
RECRUITING

München, 81377, Germany
Levine Cancer Center
RECRUITING

Charlotte, North Carolina, 28204-2990, United States
Liaoning Cancer Hospital and Institute
RECRUITING

Shenyang, Liaoning, 110042, China
Macquarie University
RECRUITING

North Ryde, New South Wales, NSW 2109, Australia
Mary Bird Perkins Cancer Center
RECRUITING

Baton Rouge, Louisiana, 70809-3738, United States
Mater Misericordiae University Hospital
RECRUITING

Dublin, D7, Ireland
Mayo Clinic Rochester
RECRUITING

Rochester, Minnesota, 55905-0001, United States
Medical University Vienna Oncology
RECRUITING

Vienna, 1090, Austria
Medizinische Universitaetsklinik
RECRUITING

Tübingen, 72076, Germany
Medizinische Universitatsklinik Innsbruck
RECRUITING

Innsbruck, 6020, Austria
Memorial Sloan Kettering Cancer Center Mskcc
RECRUITING

New York, New York, 10065-6800, United States
Monash Health
RECRUITING

Clayton, Victoria, VIC 3168, Australia
Nanfang Hospital, Southern Medical University
RECRUITING

Guangzhou, Guangdong, 510515, China
National Cancer Center (Korea)
RECRUITING

IlsandongGu GoyangSi, Gyeonggi-do, 10408, South Korea
North Shore Hospital
RECRUITING

Auckland, 0622, New Zealand
Northern Jiangsu Peoples Hospital
RECRUITING

Yangzhou, Jiangsu, 225001, China
Northern Nsw Health District
RECRUITING

Lismore, New South Wales, NSW 2480, Australia
Northwest Cancer Specialist, Pc(Us Oncology Research)
RECRUITING

Vancouver, Washington, 98684-6930, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
Odense University Hospital
RECRUITING

Odense C, 5000, Denmark
Oncology Associates of Oregon Willamette Valley Cancer Center
RECRUITING

Eugene, Oregon, 97401, United States
Oncology Hematology Care Clinical Trials, Llc
RECRUITING

Cincinnati, Ohio, 45245-1995, United States
Osp Kurfuerstendamm
RECRUITING

Berlin, 10707, Germany
Ospedale San Raffaele
RECRUITING

Milan, 20132, Italy
Penn State Milton S Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States
Perth Blood Institute
RECRUITING

West Perth, Western Australia, WA 6005, Australia
Peter Maccallum Cancer Centre
RECRUITING

Melbourne, Victoria, VIC 3000, Australia
Princess Alexandra Hospital
RECRUITING

Woolloongabba, Queensland, QLD 4102, Australia
Pusan National University Hospital
RECRUITING

Seogu, Busan Gwang'yeogsi, 49241, South Korea
Rigshospitalet
RECRUITING

Copenhagen, 2100, Denmark
Rijnstate
RECRUITING

Arnhem, 6815 AD, Netherlands
Rockingham Hospital
RECRUITING

Cooloongup, Western Australia, WA 6168, Australia
Rocky Mountain Cancer Centers (Williams) Usor
RECRUITING

Aurora, Colorado, 80012-5405, United States
Royal Cornwall Hospitalsnhs Trust
RECRUITING

Truro, TR1 3LJ, United Kingdom
Sahlgrenska University Hospital Hematology
RECRUITING

Gothenburg, 413 46, Sweden
Samsung Medical Center
RECRUITING

GangnamGu, Seoul Teugbyeolsi, 06351, South Korea
Scripps Prebys Cancer Center
RECRUITING

San Diego, California, 92103-2106, United States
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, Seoul Teugbyeolsi, 03080, South Korea
Severance Hospital Yonsei University Health System
RECRUITING

SeodaemunGu, Seoul Teugbyeolsi, 03722, South Korea
Shaanxi Provincial Peoples Hospital
RECRUITING

Xi'an, Shaanxi, 710068, China
Shandong Provincial Hospital
RECRUITING

Jinan, Shandong, 250021, China
Sidney Kimmel Comprehensive Cancer Center Washington Twp
RECRUITING

Sewell, New Jersey, 08080, United States
Skanes Universitetssjukhus I Lund
RECRUITING

Lund, 221 85, Sweden
St George Hospital
RECRUITING

Kogarah, New South Wales, NSW 2217, Australia
St Jamess Hospital
RECRUITING

Dublin, D08 NHY1, Ireland
St Vincents Hospital Melbourne
RECRUITING

Fitzroy, Victoria, VIC 3065, Australia
Stanford Cancer Institute
RECRUITING

Palo Alto, California, 94304-2205, United States
Stauferklinikum Schwabisch Gmund Kliniken Ostalb
RECRUITING

Mutlangen, 73557, Germany
Sunshine Coast Hospital and Health Service
RECRUITING

Birtinya, Queensland, QLD 4575, Australia
Suzhou Municipal Hospitalbaita Branch
RECRUITING

Suzhou, Jiangsu, 215001, China
Taizhou Hospital of Zhejiang Province (East)
RECRUITING

Taizhou, Zhejiang, 317004, China
Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37205, United States
Tennessee Oncology Greco Hainsworth Centers For Research Chattanooga
RECRUITING

Chattanooga, Tennessee, 37404, United States
Tergooi Mc
RECRUITING

Hilversum, 1212 VG, Netherlands
Texas Oncology Baylorcharles A Sammons Cancer Center
RECRUITING

Dallas, Texas, 75246-2003, United States
Texas Oncology San Antonio Medical Center Usor
RECRUITING

San Antonio, Texas, 78240-5251, United States
Texas Oncology Tyler
RECRUITING

Tyler, Texas, 75702-7522, United States
The Affiliated Hospital of Inner Mongolia Medical University
RECRUITING

Hohhot, Inner Mongolia, 010050, China
The Affiliated Hospital of Qingdao University Branch West Coast
RECRUITING

Qingdao, Shandong, 266555, China
The Affiliated Peoples Hospital of Ningbo University
RECRUITING

Ningbo, Zhejiang, 315040, China
The Alfred Hospital
RECRUITING

Melbourne, Victoria, VIC 3004, Australia
The Cancer and Hematology Centers
RECRUITING

Grand Rapids, Michigan, 49503-2563, United States
The Catholic University of Korea, Seoul St Marys Hospital
RECRUITING

SeochoGu, Seoul Teugbyeolsi, 06591, South Korea
The First Affiliated Hospital of Xiamen University
RECRUITING

Xiamen, Fujian, 361003, China
Thomas Jefferson University
RECRUITING

Philadelphia, Pennsylvania, 19107-4216, United States
Uci Health Laguna Hills
RECRUITING

Laguna Hills, California, 92653, United States
Uniklinik Koeln (Aoer)
RECRUITING

Cologne, 50937, Germany
Universidade de Campinas Centro de Hematologia E Hemoterapia
ACTIVE_NOT_RECRUITING

Campinas, 13083-878, Brazil
Universita Degli Studi Di Modena Azienda Ospedaliere Policlinco
RECRUITING

Modena, 41124, Italy
Universitaetsklinikum Ulm
RECRUITING

Ulm, 89081, Germany
Universitatsklinikum Jena Klinik Fur Innere Medizin Ii
RECRUITING

Jena, 07747, Germany
University Hospital Galway
RECRUITING

Galway, H91 YR71, Ireland
University Hospital Limerick
RECRUITING

Limerick, V94F858, Ireland
University Hospital of Aalborg
RECRUITING

Aalborg, 9000, Denmark
University Hospitals Dorset Royal Bournemouth Hospital
RECRUITING

Bournemouth, BH7 7DW, United Kingdom
University Hospitals Leuven
RECRUITING

Leuven, 3000, Belgium
University of Louisville, Brown Cancer Center
RECRUITING

Louisville, Kentucky, 40202, United States
University of Maryland Greenebaum Comprehensive Cancer Center
RECRUITING

Baltimore, Maryland, 21201-1544, United States
University of North Carolina At Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27514-4220, United States
Upmc Hillman Cancer Center(Univ of Pittsburgh)
RECRUITING

Pittsburgh, Pennsylvania, 15232-1309, United States
Uppsala Akademiska Sjukhus
RECRUITING

Uppsala, 751 85, Sweden
Uz Antwerpen
RECRUITING

Edegem, 2650, Belgium
Vall D Hebron Institute of Oncology Vhio
RECRUITING

Barcelona, 08035, Spain
Vseobecna Fakultni Nemocnice V Praze
RECRUITING

Prague, 10000, Czechia
West China Hospital, Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China
Wojewodzki Szpital Zespolony Im L Rydygiera W Toruniu
RECRUITING

Torun, 87-100, Poland
Yale University, Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06520-8028, United States
Zealand University Hospital, Roskilde
RECRUITING

Roskilde, 4000, Denmark
Zhongda Hospital Southeast University
RECRUITING

Nanjing, Jiangsu, 210009, China

Conditions

Explore the condition pages connected to this study.

CHRONIC LYMPHOCYTIC LEUKEMIA SMALL LYMPHOCYTIC LYMPHOMA