New hope for blood cancer patients when first treatment stops working

NCT ID NCT07024706

Summary

This study is testing whether a combination of two targeted drugs (acalabrutinib and venetoclax) can effectively treat patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) when their cancer returns after successful first-line treatment. The trial will enroll 80 adults whose cancer relapsed at least 2 years after completing their initial therapy. Researchers will group patients by disease risk and measure how well the treatment works and how safe it is over up to 5 years.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    Boston, Massachusetts, 02215, United States

  • Research Site

    Charlotte, North Carolina, 28204, United States

  • Research Site

    Durham, North Carolina, 27705, United States

  • Research Site

    Horn, 3580, Austria

  • Research Site

    Brno, 625 00, Czechia

  • Research Site

    Hradec Kralova, 50005, Czechia

  • Research Site

    Ostrava, 708 502, Czechia

  • Research Site

    Dublin, 7, Ireland

  • Research Site

    Dublin, D08 NHY1, Ireland

  • Research Site

    Lugo, 48022, Italy

  • Research Site

    Meldola, 47014, Italy

  • Research Site

    Milan, 20162, Italy

  • Research Site

    Padua, 35128, Italy

  • Research Site

    Roma, 00165, Italy

  • Research Site

    Rome, 00168, Italy

  • Research Site

    Torino, 10126, Italy

  • Research Site

    Bydgoszcz, 85-168, Poland

  • Research Site

    Krakow, 30-727, Poland

  • Research Site

    Lodz, 93-513, Poland

  • Research Site

    Lublin, 20-090, Poland

  • Research Site

    Warsaw, 02-172, Poland

  • Research Site

    Warsaw, 02-776, Poland

  • Research Site

    Barcelona, 08041, Spain

  • Research Site

    Barcelona, 8035, Spain

  • Research Site

    Granada, 18014, Spain

  • Research Site

    Madrid, 28031, Spain

  • Research Site

    Madrid, 28034, Spain

  • Research Site

    Madrid, 28041, Spain

  • Research Site

    Majadahonda, 28222, Spain

Conditions

Explore the condition pages connected to this study.