New combo therapies show promise for japanese CLL patients

NCT ID NCT05105841

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 23 times

Summary

This study tested two drug combinations (venetoclax plus obinutuzumab or ibrutinib) in 20 Japanese adults with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The goal was to see how well the treatments worked and how safe they were. Participants received the drugs in cycles over about a year, and doctors monitored their response and side effects.

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Contacts and locations

Locations

  • Aichi Cancer Center Hospital /ID# 238797

    Nagoya, Aichi-ken, 464-8681, Japan

  • Duplicate_Chiba Cancer Center /ID# 238839

    Chiba, Chiba, 260-8717, Japan

  • Duplicate_Hokkaido University Hospital /ID# 238377

    Sapporo, Hokkaido, 060-8648, Japan

  • Duplicate_Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital /ID# 233524

    Nagoya, Aichi-ken, 466-8650, Japan

  • Duplicate_Jichi Medical University Hospital /ID# 238434

    Shimotsuke-shi, Tochigi, 329-0498, Japan

  • Duplicate_NHO Nagoya Medical Center /ID# 233523

    Nagoya, Aichi-ken, 460-0001, Japan

  • Duplicate_Okayama University Hospital /ID# 238467

    Okayama, Okayama-ken, 700-8558, Japan

  • Duplicate_Osaka University Hospital /ID# 234037

    Suita-shi, Osaka, 565-0871, Japan

  • Duplicate_Shimane University Hospital /ID# 234076

    Izumo-shi, Shimane, 693-8501, Japan

  • Hyogo Prefectural Amagasaki General Medical Center /ID# 234082

    Amagasaki-shi, Hyōgo, 660-8550, Japan

  • Kindai University Hospital /ID# 234001

    Osakasayama-shi, Osaka, 589-8511, Japan

  • Kyushu University Hospital /ID# 238437

    Fukuoka, Fukuoka, 812-8582, Japan

  • National Cancer Center Hospital /ID# 232449

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Hospital Organization Shikoku Cancer Center /ID# 234059

    Matsuyama, Ehime, 791-0280, Japan

  • Niigata University Medical & Dental Hospital /ID# 238324

    Niigata, Niigata, 951-8520, Japan

  • The Cancer Institute Hospital Of JFCR /ID# 232450

    Koto-ku, Tokyo, 135-8550, Japan

  • Tohoku University Hospital /ID# 238433

    Sendai, Miyagi, 9808574, Japan

  • Tokai University Hospital /ID# 238970

    Isehara, Kanagawa, 259-1193, Japan

  • University Hospital Kyoto Prefectural University of Medicine /ID# 239883

    Kyoto, Kyoto, 602-8566, Japan

  • Yamagata University Hospital /ID# 234032

    Yamagata, Yamagata, 990-9585, Japan

Conditions

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