No-Clip gallbladder surgery shows promise in small trial

NCT ID NCT07473388

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new way to remove the gallbladder using a harmonic scalpel instead of metal clips to seal blood vessels and bile ducts. The trial involved 158 adults with gallstones who were scheduled for elective surgery. The goal was to see if the clipless method reduces surgery time and blood loss compared to the standard clip-based approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

harmonic scalpel (surgical device)

What this could lead to

If successful, this technique could make gallbladder removal faster and safer by eliminating the need for metal clips.

What could go wrong

This is a small, single-center trial in Pakistan, so results may not apply to other settings. The harmonic scalpel may not work as well for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholecystitis gallstones

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Services Institute of Medical Sciences

    Lahore, Punjab Province, 54000, Pakistan