No-Clip gallbladder surgery shows promise in small trial

NCT ID NCT07473388

Completed Symptom relief Sponsor: Services Hospital, Lahore Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new way to remove the gallbladder using a harmonic scalpel instead of metal clips to seal blood vessels and bile ducts. The trial involved 158 adults with gallstones who were scheduled for elective surgery. The goal was to see if the clipless method reduces surgery time and blood loss compared to the standard clip-based approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: harmonic scalpel (surgical device)
What this could lead to: If successful, this technique could make gallbladder removal faster and safer by eliminating the need for metal clips.
What could go wrong: This is a small, single-center trial in Pakistan, so results may not apply to other settings. The harmonic scalpel may not work as well for all patients.

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Conditions

The condition(s) this trial relates to.

cholecystitis gallstones

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHOLECYSTECTOMY, LAPAROSCOPIC CHOLECYSTITIS GALL STONES (& [CALCULUS - GALL BLADDER])

Contacts and locations

Locations

Services Institute of Medical Sciences

Lahore, Punjab Province, 54000, Pakistan

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