Could a single daily antibiotic dose be enough for septic abortion?
NCT ID NCT02309346
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving the antibiotic clindamycin once a day (along with gentamicin) works as well as the standard three-times-a-day regimen for treating septic abortion, a serious infection after a miscarriage or abortion. Researchers enrolled 202 women and measured cure rates, defined as reduced pain, bleeding, and no fever for 48 hours. The goal was to see if a simpler dosing schedule could be just as effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Clindamycin and gentamicin (antibiotics given intravenously)
- What this could lead to
- If successful, this could simplify treatment for septic abortion by showing that a once-daily antibiotic dose works as well as the standard three-times-a-day regimen.
- What could go wrong
- This is a completed phase 4 trial, but results may not apply to all patients or settings. The definition of cure is based on clinical signs, and some patients were lost to follow-up, which could affect reliability.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90035-003, Brazil