Could a single daily antibiotic dose be enough for septic abortion?
NCT ID NCT02309346
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving the antibiotic clindamycin once a day (along with gentamicin) works as well as the standard three-times-a-day regimen for treating septic abortion, a serious infection after a miscarriage or abortion. Researchers enrolled 202 women and measured cure rates, defined as reduced pain, bleeding, and no fever for 48 hours. The goal was to see if a simpler dosing schedule could be just as effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Clindamycin and gentamicin (antibiotics given intravenously)
What this could lead to
If successful, this could simplify treatment for septic abortion by showing that a once-daily antibiotic dose works as well as the standard three-times-a-day regimen.
What could go wrong
This is a completed phase 4 trial, but results may not apply to all patients or settings. The definition of cure is based on clinical signs, and some patients were lost to follow-up, which could affect reliability.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90035-003, Brazil