New heart valve repair device shows promise in leaky valve patients
NCT ID NCT03170349
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 32 times
Summary
This study tested a new device called the Edwards PASCAL system, which repairs leaky mitral heart valves using a thin tube inserted through a vein, avoiding open-heart surgery. It included 124 adults with moderate-to-severe mitral regurgitation and heart failure. The main goals were to see if the device is safe and effectively reduces the valve leak, with follow-up over one year.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MITRAL VALVE REGURGITATION are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Carolinas Medical Center
Charlotte, North Carolina, 28203, United States
-
Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
-
Henry Ford Hospital
Detroit, Michigan, 48202, United States
-
Hygeia Hospital
Athens, 15123, Greece
-
Inselspital, University Hospital Bern
Bern, 3010, Switzerland
-
Metro North Hospital & Health Service, The Prince Charles Hospital
Brisbane, Chermside, QLD 4032, Australia
-
Morristown Medical Center
Morristown, New Jersey, 07960, United States
-
NorthShore University HealthSystem
Evanston, Illinois, 60201, United States
-
San Rafaelle Hospital
Milan, 20132, Italy
-
St Michael Hospital
Toronto, Ontario, M5B-1W8, Canada
-
St. Paul's Hospital, Providence Health Care Research Institute
Vancouver, British Columbia, V6E 1M7, Canada
-
Sunnybrook Hospital
Toronto, Ontario, M4N 3M5, Canada
-
Sydney Local Health District, Royal Prince Alfred Hospital
Camperdown, New South Wales, 2050, Australia
-
The Heart Hospital Baylor Plano
Plano, Texas, 75093, United States
-
Universitaetsklinikum Bonn, Medizinische Klinik II, Kardiologie
Bonn, 53127, Germany
-
University of Colorado Denver
Aurora, Colorado, 80045, United States
-
University of Virginia Health System
Charlottesville, Virginia, 22908, United States
Conditions
Explore the condition pages connected to this study.