New shot aims to prevent dangerous clots in High-Risk patients

NCT ID NCT07430397

First seen Feb 27, 2026 · Last updated May 04, 2026 · Updated 12 times

Summary

This early-stage study tests a single injection of a new drug called CITY-FXI in healthy adults and those with Factor V Leiden or prothrombin G20210A mutation, which increase blood clot risk. The goal is to see if the drug is safe and how it works in the body. About 128 participants will receive either the drug or a placebo, and researchers will monitor for side effects and measure drug levels in the blood.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Richmond Pharmacology

    RECRUITING

    London, SE1 1YR, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.