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Blood test may reveal hidden cancer cells in head and neck tumors

NCT ID NCT02892786

Diagnosis Sponsor: Institut de Cancérologie de Lorraine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This trial investigates whether a blood test can detect circulating tumor cells (CTCs) in patients with advanced head and neck cancer. Researchers will take blood samples before, during, and after surgery, and use two different methods to count these cells. The goal is to see if the presence of CTCs can help predict whether the cancer will come back within two years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Blood test for circulating tumor cells using RT-PCR and CellSearch method
What this could lead to
If successful, this could lead to a simple blood test that helps predict relapse in head and neck cancer patients.
What could go wrong
This is a small, early-stage study, and the detection methods may not prove reliable or change patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Dec 2010

Finished

Apr 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Patient with head and neck squamous cell cancer stage III or IV histologically proven * Patient naive to any prior therapy * Patient with operate cancer and resectable tumor * Hemoglobin ≥ 10g / dL * Performance status ≤ 2 * Ability to provide written informed consent * Patient's legal capacity to consent to study participation Exclusion Criteria: * Other previous histology tumors * Medical conditions or acute or chronic severe psychiatric disorders * Deprived of liberty or under supervision

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma Neoplastic Cells, Circulating

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Head and neck cancer

Contacts and locations

Locations

  • Institut de Cancérologie de Lorraine

    Vandœuvre-lès-Nancy, 54519, France

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