Scientists hunt for genes to reverse aging body clock
NCT ID NCT04086589
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at why our internal body clock weakens with age. Researchers will take blood from 20 healthy young adults (ages 20-35) and 20 healthy older adults (ages 70-85) and add it to lab-grown cells to see how it affects their daily rhythms. The goal is to find genes that could restore a youthful circadian rhythm, which may later be tested in animals.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could point toward genes that restore healthy sleep-wake cycles in older adults.
- What could go wrong
- This is a small, early exploratory study that is currently suspended. It only uses lab cells and animal models, so any findings may not apply to humans.
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Contacts and locations
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Locations
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University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania, 19104, United States
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