Scientists hunt for early warning signs of kidney failure in rare genetic diseases

NCT ID NCT04874909

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study collected blood and urine samples from 240 people with ciliopathies—rare genetic disorders that often lead to kidney failure. Researchers analyzed these samples to find biological markers that could predict how the disease will progress. The goal is to develop a test that helps doctors identify patients at highest risk for kidney problems, allowing for earlier and more personalized care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a test that predicts which ciliopathy patients will develop kidney failure, enabling earlier monitoring and care.
What could go wrong
This is an observational study, not a treatment trial. The findings may not lead to a usable test, and results may not apply to all ciliopathy types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, 75015, France

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