New hope for kids with devastating brain cancer? early trial tests novel drug combo

NCT ID NCT01165333

Summary

This early-stage study aimed to find the safest dose of an experimental drug called Cilengitide when given alongside standard radiation therapy. It involved 32 children and young adults newly diagnosed with a rare and aggressive brain stem tumor (DIPG), which has very poor survival rates. The main goal was to see if the drug-radiation combination was tolerable, not to cure the disease, as a first step toward finding better treatments.

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Contacts and locations

Locations

  • CHU

    Toulouse, 33059, France

  • CHU, Hôpital d'Enfants de la Timone

    Marseille, 13385, France

  • Centre Hospitalier Universitaire de Nantes

    Nantes, 44093, France

  • Centre Léon Bérard

    Lyon, 69373, France

  • Centre Oscar Lambret

    Lille, 59020, France

  • Hôpital des Enfants, Groupe Hospitalier

    Bordeaux, 33076, France

  • Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

  • Institut Curie

    Paris, 75231, France

  • Institut Gustave-Roussy

    Villejuif, 94805, France

Conditions

Explore the condition pages connected to this study.